Description

2-(4-Bromobenzyl)-2,5-Diazabicyclo[2.2.1]Heptane is a high-purity, advanced pharmaceutical intermediate featuring a unique bridged diazabicyclic structure. This compound is valued for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting neurological and psychiatric disorders. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, where its precise stereochemistry and functional groups are essential for biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of central nervous system (CNS) targeting drugs and other specialized APIs.
• Medicinal Chemistry Research: Used as a versatile scaffold in drug discovery programs for structure-activity relationship (SAR) studies.
• Ligand Synthesis: Serves as a core structure for creating novel ligands in receptor binding assays and diagnostic agent development.
• Chemical Biology Probes: Employed in the development of tool compounds for studying biological pathways and enzyme functions.
• Custom Synthesis: A starting material for the contract manufacturing of complex, high-value molecules for clinical trials.

Basic Information

Product Name	2-(4-Bromobenzyl)-2,5-Diazabicyclo[2.2.1]Heptane
CAS No.	845866-72-0
Molecular Formula	C13H17BrN2
Molecular Weight	281.19 g/mol
Synonyms	2-[(4-Bromophenyl)methyl]-2,5-diazabicyclo[2.2.1]heptane; 2-(4-Bromobenzyl)-2,5-diazabicyclo[2.2.1]heptane; 2,5-Diazabicyclo[2.2.1]heptane, 2-[(4-bromophenyl)methyl]-; 845866-72-0; 2-(p-Bromobenzyl)-2,5-diazabicyclo[2.2.1]heptane; 2-(4-Bromobenzyl)-2,5-diazabicyclo[2.2.1]heptane (CAS 845866-72-0); 2-(4-Bromobenzyl)-2,5-diazabicyclo[2.2.1]heptane, 97%
EINECS	Contact for details

Quality Control

Our 2-(4-Bromobenzyl)-2,5-Diazabicyclo[2.2.1]Heptane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our production adheres to cGMP guidelines where applicable, ensuring reliability for research and pre-clinical development phases.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.