Description

2-(Methylamino)Benzotrifluoride Hydrochloride is a high-purity organic intermediate featuring a benzotrifluoride core substituted with a methylamino group. This compound is valued for its trifluoromethyl group, which imparts unique physicochemical properties such as enhanced lipophilicity and metabolic stability, making it a critical building block in advanced synthesis. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS and metabolic diseases.
• Agrochemical Synthesis: Used as a precursor for developing advanced pesticides and herbicides, where the trifluoromethyl group can improve biological activity and environmental profile.
• Material Science Research: Serves as a monomer or functionalizing agent in the synthesis of specialty polymers and advanced organic electronic materials.
• Chemical Research & Development: Employed in academic and industrial R&D labs for method development and as a standard in analytical studies.
• Ligand and Catalyst Preparation: Useful for constructing complex ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.

Basic Information

Product Name	2-(Methylamino)Benzotrifluoride Hydrochloride
CAS No.	845866-58-2
Molecular Formula	C8H9F3N·HCl
Molecular Weight	215.62 g/mol
Synonyms	2-(Methylamino)-α,α,α-trifluorotoluene Hydrochloride; N-Methyl-2-(trifluoromethyl)aniline Hydrochloride; 1-Methylamino-2-(trifluoromethyl)benzene Hydrochloride; 2-(Trifluoromethyl)-N-methylaniline Hydrochloride; 2-Methylaminobenzotrifluoride HCl; (2-(Methylamino)phenyl)trifluoromethane Hydrochloride; α,α,α-Trifluoro-2-(methylamino)toluene Hydrochloride
EINECS	Contact for details

Quality Control

Our 2-(Methylamino)Benzotrifluoride Hydrochloride is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.