Description

Benzenemethanamine, 4-Bromo-2-Fluoro-.Alpha.-Methyl-, Hydrochloride (1:1), (.Alpha.R)- is a high-purity chiral amine building block, specifically the (R)-enantiomer of a halogenated benzylamine derivative. This compound is of significant value in pharmaceutical research and development, serving as a critical intermediate for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecules with specific stereochemistry. The product is supplied as a hydrochloride salt to enhance its stability and handling properties.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of potential drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides where specific stereochemistry influences biological activity.
• Ligand Synthesis: Precursor for creating chiral ligands used in asymmetric catalysis.
• Chemical Biology: Useful as a molecular probe or tag in biochemical studies due to its halogenated aromatic structure.
• Custom Synthesis: Serves as a starting material for contract research organizations (CROs) and custom synthesis houses for client-specific projects.
• Academic Research: Employed in university laboratories for methodological development in organic synthesis and stereochemistry.

Basic Information

Product Name	Benzenemethanamine, 4-Bromo-2-Fluoro-.Alpha.-Methyl-, Hydrochloride (1:1), (.Alpha.R)-
CAS No.	845829-91-6
Molecular Formula	C8H10BrClFN
Molecular Weight	254.53 g/mol
Synonyms	(R)-1-(4-Bromo-2-fluorophenyl)ethanamine hydrochloride; (αR)-α-Methyl-4-bromo-2-fluorobenzenemethanamine hydrochloride; 4-Bromo-2-fluoro-(R)-α-methylbenzylamine hydrochloride; (R)-1-(4-Bromo-2-fluorophenyl)ethylamine HCl; (R)-4-Bromo-2-fluoro-α-methylbenzylamine hydrochloride; Benzenemethanamine, 4-bromo-2-fluoro-α-methyl-, hydrochloride, (αR)-; (R)-4-Bromo-2-fluoro-α-methylbenzylamine hydrochloride
EINECS	Contact for details

Quality Control

Our Benzenemethanamine, 4-Bromo-2-Fluoro-.Alpha.-Methyl-, Hydrochloride (1:1), (.Alpha.R)- is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity suitable for research and development applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.