Description

5-(3,4-Difluorophenyl)-5-Oxovaleric Acid is a high-purity fluorinated organic acid building block of significant interest in advanced chemical synthesis. Its molecular structure, featuring a difluorophenyl moiety and a terminal carboxylic acid, makes it a versatile intermediate for constructing complex molecules with tailored properties. This compound is primarily sought by R&D and production teams in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) and metabolic diseases.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides, where the difluorophenyl group can enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, contributing to improved performance and durability.
• Polymer Modification: Employed to introduce fluorine atoms into polymer backbones or side chains, altering material properties like chemical resistance, thermal stability, and surface energy.
• Organic Synthesis & Research: A valuable reagent for academic and industrial chemists exploring new carbon-carbon and carbon-heteroatom bond-forming reactions involving fluorinated aromatics.

Basic Information

Product Name	5-(3,4-Difluorophenyl)-5-Oxovaleric Acid
CAS No.	845790-46-7
Molecular Formula	C11H10F2O3
Molecular Weight	228.19 g/mol
Synonyms	5-Oxo-5-(3,4-difluorophenyl)pentanoic acid; 4-(3,4-Difluorobenzoyl)butyric acid; 3,4-Difluoro-γ-oxobenzenebutanoic acid; γ-Oxo-3,4-difluorobenzenebutanoic acid; 5-(3,4-Difluorobenzoyl)valeric acid; 845790-46-7; 5-(3,4-Difluorophenyl)-5-oxopentanoic acid
EINECS	Contact for details

Quality Control

Every batch of 5-(3,4-Difluorophenyl)-5-Oxovaleric Acid is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay and impurity profiles. Our quality commitment supports compliance with cGMP and ISO standards for demanding applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly closed when not in use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.