Description

3-Bromo-3'-Fluorobiphenyl is a high-purity halogenated biphenyl derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring bromine and fluorine substituents at specific positions, makes it an invaluable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and plant growth regulators, leveraging the fluorine atom for enhanced bioactivity and metabolic stability.
• Ligand & Catalyst Development: Serves as a core structure for synthesizing specialized ligands used in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and organometallic catalysts.
• Material Science Research: Building block for organic electronic materials, such as semiconductors for OLEDs (Organic Light-Emitting Diodes) and OFETs (Organic Field-Effect Transistors).
• Chemical Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation in chromatographic analysis.

Basic Information

Product Name	3-Bromo-3'-Fluorobiphenyl
CAS No.	844856-60-6
Molecular Formula	C₁₂H₈BrF
Molecular Weight	251.09 g/mol
Synonyms	1-Bromo-3-(3-fluorophenyl)benzene; [1,1'-Biphenyl]-3-bromo-3'-fluoro; 3-Bromo-3'-fluoro-1,1'-biphenyl; 3'-Fluoro-3-bromobiphenyl; (3-Bromophenyl)(3-fluorophenyl); 3-Fluoro-3'-bromobiphenyl
EINECS	Contact for details

Quality Control

Our 3-Bromo-3'-Fluorobiphenyl is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our commitment to quality supports compliance with cGMP and ICH guidelines for use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH limits
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.