Description

(As)-α-Cyclopropylbenzenemethanamine Hydrochloride is a high-purity chiral amine building block and pharmaceutical intermediate. This compound is critical for research and development in medicinal chemistry, particularly for the synthesis of novel active pharmaceutical ingredients (APIs) with specific stereochemical requirements. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers focused on developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, infectious diseases, and other therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to explore new chemical entities.
• Asymmetric Synthesis: Employed as a building block in catalytic asymmetric reactions to construct complex molecules with high enantiomeric purity.
• Reference Standard: Functions as a certified reference material (CRM) for analytical method development and quality control in pharmaceutical analysis.
• Agrochemical Research: Potential application as an intermediate in the development of novel crop protection agents with specific stereochemistry.
• Academic Research: Utilized in university and institutional laboratories for studies in organic synthesis, catalysis, and chemical biology.

Basic Information

Product Name	(As)-α-Cyclopropylbenzenemethanamine Hydrochloride
CAS No.	844470-80-0
Molecular Formula	C11H16ClN
Molecular Weight	197.70 g/mol
Synonyms	α-Cyclopropylbenzylamine Hydrochloride; (1R)-1-Cyclopropyl-1-phenylethanamine Hydrochloride; (R)-1-Cyclopropyl-1-phenylethylamine HCl; (R)-α-Cyclopropylbenzylamine Hydrochloride; (R)-1-Phenyl-1-cyclopropylethylamine Hydrochloride; Benzenemethanamine, α-cyclopropyl-, hydrochloride, (αR)-; (As)-1-Cyclopropyl-1-phenylethanamine Hydrochloride
EINECS	Contact for details

Quality Control

Our (As)-α-Cyclopropylbenzenemethanamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) determination, to ensure it meets the high-purity standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.