Description

1-(4-Bromo-Phenyl)-2,2,2-Trifluoro-Ethylamine Hydrochloride is a high-purity, advanced pharmaceutical intermediate characterized by its distinct aromatic bromine and trifluoromethyl motifs. This compound is of significant commercial value for its role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new drug candidates and high-value fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of new drug molecules, especially those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Research: Used in developing advanced pesticides and herbicides, where the bromophenyl and trifluoroethyl groups contribute to biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and organometallic chemistry.
• Fluorinated Compound Synthesis: An essential reagent for introducing the trifluoroethylamine moiety into complex organic molecules, enhancing their metabolic stability and lipophilicity.
• Life Science Research: Employed in biochemical and pharmacological studies as a reference standard or a probe for investigating enzyme inhibition and receptor binding.
• Material Science Precursor: Potential use in the synthesis of fluorinated polymers and advanced organic materials with specific electronic or surface properties.

Basic Information

Product Name	1-(4-Bromo-Phenyl)-2,2,2-Trifluoro-Ethylamine Hydrochloride
CAS No.	842169-72-6
Molecular Formula	C8H8BrF3N·HCl
Molecular Weight	294.51 g/mol
Synonyms	4-Bromo-α-(trifluoromethyl)benzylamine hydrochloride; 1-(4-Bromophenyl)-2,2,2-trifluoroethanamine hydrochloride; (4-Bromophenyl)(trifluoromethyl)methylamine hydrochloride; α-(Trifluoromethyl)-4-bromobenzylamine HCl; 1-(4-Bromophenyl)-2,2,2-trifluoroethylamine HCl; 4-Bromo-α,α,α-trifluoroethylbenzylamine hydrochloride; p-Bromo-α-(trifluoromethyl)benzylamine hydrochloride
EINECS	Contact for details

Quality Control

Our 1-(4-Bromo-Phenyl)-2,2,2-Trifluoro-Ethylamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.