Description

5-Bromoquinazolin-6-Ylthiourea is a specialized heterocyclic organic compound that serves as a high-value building block in advanced chemical synthesis. Its unique molecular structure, featuring bromine and thiourea functional groups on a quinazoline core, makes it a critical intermediate for developing novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily sought by research institutions and industrial R&D departments focused on medicinal chemistry, drug discovery, and the development of crop protection agents.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of kinase inhibitors and other targeted therapeutic agents for oncology and inflammatory diseases.
• Agrochemical Research: Used in developing novel fungicides and herbicides due to its bioactive quinazoline-thiourea scaffold.
• Chemical Biology Probe: Serves as a scaffold for creating molecular probes to study enzyme function and cellular signaling pathways.
• Organic Synthesis Building Block: Employed in heterocyclic and medicinal chemistry for constructing complex molecular libraries.
• Material Science Research: Investigated as a potential monomer or additive for creating specialty polymers with specific electronic or binding properties.

Basic Information

Product Name	5-Bromoquinazolin-6-Ylthiourea
CAS No.	842138-74-3
Molecular Formula	C9H7BrN4S
Molecular Weight	283.15 g/mol
Synonyms	6-Thioureido-5-bromoquinazoline; 5-Bromo-6-isothiocyanatoquinazoline (precursor); 5-Bromo-6-thiocyanatoquinazoline; N-(5-Bromoquinazolin-6-yl)thiourea; 5-Bromo-6-quinazolinylthiourea; 842138-74-3; 5-Brom-6-chinolylthiocarbamid (German); Thiocarbamide, N-(5-bromo-6-quinazolinyl)-
EINECS	Contact for details

Quality Control

Every batch of 5-Bromoquinazolin-6-Ylthiourea is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development applications. A detailed Certificate of Analysis (COA) specifying purity, identity, and impurity profiles by HPLC, NMR, and mass spectrometry is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.