Description

1,4-Difluoro-2-(1,3-Dioxolan-2-Ylmethyl)Benzene is a high-purity fluorinated aromatic building block featuring a protected aldehyde functionality. This compound is valued for its role as a versatile synthetic intermediate in advanced organic synthesis, enabling the introduction of fluorine atoms and subsequent functional group manipulation. It is primarily sought by R&D and production chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those requiring fluorinated aromatic cores for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atoms and reactive handle contribute to improved efficacy and environmental profile.
• Material Science Research: Serves as a monomer or precursor in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Organic Synthesis Reagent: Employed in academic and industrial laboratories for constructing complex molecular architectures via cross-coupling reactions and other transformations.
• Fluorine Chemistry Studies: Acts as a model substrate for investigating new fluorination methodologies and the properties of fluorinated compounds.

Basic Information

Product Name	1,4-Difluoro-2-(1,3-Dioxolan-2-Ylmethyl)Benzene
CAS No.	842123-88-0
Molecular Formula	C11H10F2O2
Molecular Weight	212.19 g/mol
Synonyms	2,5-Difluoro-α-(1,3-dioxolan-2-yl)-o-xylene; 1,4-Difluoro-2-((1,3-dioxolan-2-yl)methyl)benzene; 2,5-Difluorobenzaldehyde Ethylene Acetal; 2-(2,5-Difluorobenzyl)-1,3-dioxolane; Benzene, 1,4-difluoro-2-(1,3-dioxolan-2-ylmethyl)-; 2,5-Difluorophenylacetaldehyde Ethylene Acetal
EINECS	Contact for details

Quality Control

Our 1,4-Difluoro-2-(1,3-Dioxolan-2-Ylmethyl)Benzene is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high standards, including cGMP development and commercial-scale production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.