Description

3-Nitro-(S)-Alphamethylbenzylamine.Hcl is a high-purity chiral amine derivative, specifically the hydrochloride salt of the (S)-enantiomer. This compound serves as a critical chiral building block and resolving agent in the synthesis of complex, optically active molecules. It is essential for research and production in the pharmaceutical and fine chemical industries, where precise stereochemistry is paramount for drug efficacy and material properties.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the asymmetric synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) drugs and other therapeutics requiring high enantiomeric purity.
• Chiral Resolution Agent: Used to separate racemic mixtures of acids or other compounds via diastereomeric salt formation, enabling the isolation of single enantiomers.
• Catalyst Ligand Precursor: Employed in the development of chiral ligands for asymmetric catalysis, enhancing the efficiency and selectivity of chemical transformations.
• Fine Chemical Synthesis: Integral to the production of specialty chemicals, agrochemicals, and advanced materials where the introduction of a chiral nitrobenzylamine moiety is required.
• Academic & Industrial R&D: A valuable reference standard and starting material for method development and discovery chemistry in both academic and corporate research laboratories.

Basic Information

Product Name	3-Nitro-(S)-Alphamethylbenzylamine.Hcl
CAS No.	839709-98-7
Molecular Formula	C9H13ClN2O2
Molecular Weight	216.67 g/mol
Synonyms	(S)-1-(3-Nitrophenyl)ethylamine hydrochloride; (S)-α-Methyl-3-nitrobenzylamine hydrochloride; (S)-1-(3-Nitro-phenyl)-ethylamine HCl; (S)-3-Nitro-α-methylbenzylamine HCl; (S)-3-Nitroamphetamine hydrochloride (Note: for chemical reference); (S)-1-(m-Nitrophenyl)ethylamine hydrochloride; (S)-3-Nitro-1-phenylethylamine hydrochloride
EINECS	Contact for details

Quality Control

Our 3-Nitro-(S)-Alphamethylbenzylamine.Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity (HPLC), assay, and impurity profiling, to ensure it meets the high standards required for pharmaceutical and advanced synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with customer specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.