Description

3-Iodo-8-Methoxy-1H-Quinolin-4-One is a high-purity, functionalized quinolinone derivative of significant interest in advanced organic synthesis. This compound serves as a critical synthetic intermediate and building block for the development of novel pharmacologically active molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, particularly for the synthesis of complex heterocyclic compounds targeting various therapeutic areas.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting kinase inhibition or other enzyme-related pathways.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Sonogashira) and other transformations to construct complex molecular architectures.
• Agrochemical Research: Potential intermediate in the development of new active ingredients for crop protection products.
• Material Science: Investigated as a component for the synthesis of organic semiconductors or fluorescent materials due to the quinolinone core.
• Contract Research & Development (CRO): Supplied to CROs and custom synthesis laboratories for client-specific research projects.

Basic Information

Product Name	3-Iodo-8-Methoxy-1H-Quinolin-4-One
CAS No.	835914-45-9
Molecular Formula	C₁₀H₈INO₂
Molecular Weight	301.08 g/mol
Synonyms	3-Iodo-8-methoxy-4-quinolone; 8-Methoxy-3-iodo-1H-quinolin-4-one; 4(1H)-Quinolinone, 3-iodo-8-methoxy-; 3-Iodo-8-methoxyquinolin-4(1H)-one; 835914-45-9; AI3-52325; ZINC000103254509
EINECS	Contact for details

Quality Control

Every batch of 3-Iodo-8-Methoxy-1H-Quinolin-4-One is manufactured and tested under strict quality management protocols. We ensure compliance with high-purity standards suitable for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and consistency for your critical work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.