Description

C-[1-(1-Phenyl-Ethyl)-Pyrrolidin-3-Yl]-Methylamine is a high-purity, advanced pharmaceutical intermediate featuring a unique chiral pyrrolidine scaffold. This compound is valued for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and receptor-targeted therapeutics. It is essential for research institutions and pharmaceutical manufacturers engaged in the development of novel drug candidates requiring sophisticated nitrogen-containing heterocycles.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and commercial synthesis of novel APIs.
• Neurological Drug Discovery: Used in the development of compounds targeting dopamine, serotonin, or sigma receptors for CNS disorders.
• Asymmetric Synthesis: Serves as a chiral amine building block or ligand precursor in catalytic asymmetric reactions.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• Process Chemistry & Scale-up: Utilized in the development and optimization of scalable synthetic routes for pharmaceutical production.

Basic Information

Product Name	C-[1-(1-Phenyl-Ethyl)-Pyrrolidin-3-Yl]-Methylamine
CAS No.	835886-98-1
Molecular Formula	C14H22N2
Molecular Weight	218.34 g/mol
Synonyms	(3-Aminomethyl)-1-(1-phenylethyl)pyrrolidine; 1-(1-Phenylethyl)-3-(aminomethyl)pyrrolidine; 3-[(1-Phenylethyl)amino]methylpyrrolidine; C-[1-(1-Phenyl-Ethyl)-Pyrrolidin-3-Yl]-Methylamine; (R/S)-C-[1-(1-Phenyl-Ethyl)-Pyrrolidin-3-Yl]-Methylamine; 1-(α-Methylbenzyl)-3-(aminomethyl)pyrrolidine
EINECS	Contact for details

Quality Control

Our C-[1-(1-Phenyl-Ethyl)-Pyrrolidin-3-Yl]-Methylamine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Production adheres to cGMP (current Good Manufacturing Practice) guidelines where applicable. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles, available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.