Description

3,6-Methanonaphth[2,3-B]Oxirene-2,7-Diol,1A,2,2A,3,6,6A,7,7A-Octahydro-,(1Ar,2S,2Ar,3R,6S,6Ar,7R,7As)-Rel-(9Ci) is a complex, stereochemically defined polycyclic compound featuring a methano-bridged naphthalene core integrated with an oxirene (epoxide) moiety. This unique molecular architecture makes it a valuable chiral intermediate and building block for advanced synthetic chemistry, particularly in the development of pharmaceuticals and specialty materials. It is primarily sought by research institutions and fine chemical manufacturers engaged in the synthesis of novel active pharmaceutical ingredients (APIs) and complex organic molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral precursor in the multi-step synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders or with specific stereochemical requirements.
• Organic Synthesis Building Block: Utilized in advanced organic reactions, including ring-opening polymerizations or cascade cyclizations, to construct intricate polycyclic frameworks found in natural products and functional materials.
• Asymmetric Catalysis Research: Acts as a substrate or ligand precursor in the development and testing of new asymmetric catalytic systems due to its multiple stereocenters and rigid structure.
• Material Science Research: Investigated for the development of novel polymers or specialty chemicals with unique optical or mechanical properties derived from its fused ring system.
• Reference Standard: Used as a high-purity analytical standard in quality control laboratories for method development and validation in pharmaceutical analysis.

Basic Information

Item	Details
Product Name	3,6-Methanonaphth[2,3-B]Oxirene-2,7-Diol,1A,2,2A,3,6,6A,7,7A-Octahydro-,(1Ar,2S,2Ar,3R,6S,6Ar,7R,7As)-Rel-(9Ci)
CAS No.	835611-74-0
Molecular Formula	C13H14O3
Molecular Weight	218.25 g/mol
Synonyms	(1aR,2S,2aR,3R,6S,6aR,7R,7aS)-rel-1a,2,2a,3,6,6a,7,7a-Octahydro-3,6-methanonaphth[2,3-b]oxirene-2,7-diol; rel-(1aR,2S,2aR,3R,6S,6aR,7R,7aS)-1a,2,2a,3,6,6a,7,7a-Octahydro-3,6-methanonaphth[2,3-b]oxirene-2,7-diol; 3,6-Methanonaphth[2,3-b]oxirene-2,7-diol, 1a,2,2a,3,6,6a,7,7a-octahydro-, (1aR,2S,2aR,3R,6S,6aR,7R,7aS)-rel-; Polycyclic Oxirene Diol Intermediate; Chiral Methanonaphthoxirene Diol
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for this advanced intermediate, ensuring batch-to-batch consistency and high purity. Production adheres to cGMP guidelines where applicable, and all materials are fully characterized using advanced analytical techniques including NMR, HPLC, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept in a cool, dry place. For long-term storage, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature of 15-25°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.