Description

6-Chloro-3-Fluoroquinoline-2-Carboxylic Acid is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound matters as a key intermediate in the development of novel active pharmaceutical ingredients (APIs), particularly within the quinolone and fluoroquinolone antibiotic classes. Pharmaceutical research and development teams, as well as fine chemical manufacturers serving the agrochemical and material science sectors, require this specific carboxylic acid derivative for its precise reactivity and structural features.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of next-generation fluoroquinolone antibiotics and other bioactive molecules.
• Agrochemical Research: Used in developing novel herbicides and pesticides, leveraging the quinolone core for targeted biological activity.
• Material Science: Serves as a building block for creating specialized ligands, dyes, and functional organic materials.
• Chemical Synthesis: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Academic & Contract Research: Utilized in university and CRO laboratories for exploratory research and custom synthesis projects.

Basic Information

Product Name	6-Chloro-3-Fluoroquinoline-2-Carboxylic Acid
CAS No.	834884-08-1
Molecular Formula	C₁₀H₅ClFNO₂
Molecular Weight	225.60 g/mol
Synonyms	6-Chloro-3-fluoroquinoline-2-carboxylic acid; 2-Quinolinecarboxylic acid, 6-chloro-3-fluoro-; 6-Chloro-3-fluoro-2-quinolinecarboxylic acid; 834884-08-1; 6-Chloro-3-fluoro-quinoline-2-carboxylic acid; 6-Chloro-3-fluoro-2-carboxyquinoline; 3-Fluoro-6-chloroquinoline-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our 6-Chloro-3-Fluoroquinoline-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles where applicable, supporting our clients' regulatory and research needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The product is compatible with strong acids and organic solvents but should be kept away from incompatible materials. Keep the container sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.