Description

2,8-Dibromo-3-Fluoroquinoline is a halogenated quinoline derivative, a versatile and high-value building block in advanced organic synthesis. Its core value lies in its unique substitution pattern, which enables precise molecular modifications critical for developing novel compounds. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to create active ingredients with targeted properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in developing fluorinated and brominated bioactive molecules for oncology and antimicrobial applications.
• Agrochemical Synthesis: Used to construct complex heterocyclic cores for next-generation herbicides, fungicides, and pesticides, leveraging the fluorine and bromine atoms for enhanced activity and stability.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic light-emitting diodes (OLEDs).
• Chemical Biology Probes: Employed in the design and synthesis of fluorescent probes or molecular tags due to the quinoline scaffold's inherent photophysical properties.
• Academic & R&D Laboratories: A valuable reagent for methodological studies in cross-coupling reactions, halogen dance chemistry, and other advanced synthetic transformations.

Basic Information

Product Name	2,8-Dibromo-3-Fluoroquinoline
CAS No.	834884-04-7
Molecular Formula	C9H4Br2FN
Molecular Weight	304.94 g/mol
Synonyms	3-Fluoro-2,8-dibromoquinoline; 2,8-Dibromo-3-fluoroquinoline; Quinoline, 2,8-dibromo-3-fluoro-; 834884-04-7; FChem; AKOS; Ambeed; 3-Fluoro-2,8-dibromoquinoline (CAS 834884-04-7)
EINECS	Contact for details

Quality Control

Our 2,8-Dibromo-3-Fluoroquinoline is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC, GC, and NMR, to verify identity and purity. A Certificate of Analysis (COA) is supplied with every shipment, detailing all relevant specifications. Our quality management system is designed to meet the rigorous demands of research and commercial-scale synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is sensitive to light and should be handled under appropriate conditions to maintain stability. Keep away from strong bases and fluorides.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.