Description

2-Bromo-6-Chloro-3-Fluoroquinoline is a high-purity, multi-halogenated quinoline derivative serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in its unique halogen substitution pattern, which provides distinct reactivity for constructing complex molecular architectures. This compound is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers focused on developing novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel quinolone-based antibiotics and other therapeutic agents.
• Agrochemical Research: Used in the development of new fungicides and herbicides, leveraging the bioactive quinoline core.
• Material Science: Serves as a precursor for organic electronic materials and functional dyes due to its halogenated aromatic structure.
• Chemical Synthesis: Acts as a versatile scaffold for cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce complex substituents.
• Academic & R&D: Employed in university and institutional laboratories for methodological studies and novel compound library generation.

Basic Information

Product Name	2-Bromo-6-Chloro-3-Fluoroquinoline
CAS No.	834884-00-3
Molecular Formula	C9H4BrClFN
Molecular Weight	260.49 g/mol
Synonyms	2-Bromo-6-chloro-3-fluoroquinoline; 3-Fluoro-2-bromo-6-chloroquinoline; Quinoline, 2-bromo-6-chloro-3-fluoro-; 834884-00-3; 2-Bromo-6-chloro-3-fluoro-quinoline; 6-Chloro-2-bromo-3-fluoroquinoline
EINECS	Contact for details

Quality Control

Our 2-Bromo-6-Chloro-3-Fluoroquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. The product is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.