Description

2-Bromo-3-Fluoroquinoline is a high-value, multi-functional halogenated quinoline derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in enabling the precise construction of complex molecular architectures, particularly for active pharmaceutical ingredients (APIs) and functional materials. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries who require reliable, high-purity intermediates for their synthetic pathways.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially those targeting infectious diseases, cancer, and central nervous system disorders.
• Agrochemical Research: Used to develop new generations of fungicides and herbicides by incorporating the quinoline scaffold with halogen substituents for enhanced bioactivity.
• Material Science: Serves as a monomer or functionalizing agent in the creation of organic semiconductors, liquid crystals, and fluorescent dyes.
• Chemical Synthesis: Versatile reagent for cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic substitution, enabling diverse molecular diversification.
• Academic & Contract Research: Fundamental building block for methodological development and discovery chemistry in university and CRO laboratories.

Basic Information

Product Name	2-Bromo-3-Fluoroquinoline
CAS No.	834883-99-7
Molecular Formula	C9H5BrFN
Molecular Weight	226.05 g/mol
Synonyms	3-Fluoro-2-bromoquinoline; Quinoline, 2-bromo-3-fluoro-; 2-Bromo-3-fluoro-quinoline; 834883-99-7; 3-Fluoro-2-bromoquinoline; 2-Bromo-3-fluoroquinoline; 2-Brom-3-fluor-chinolin (German); 2-ブロモ-3-フルオロキノリン (Japanese)
EINECS	Contact for details

Quality Control

Every batch of our 2-Bromo-3-Fluoroquinoline is manufactured and tested under strict quality management systems to ensure consistency and reliability for your critical applications. We provide comprehensive analytical data including HPLC purity, identity confirmation (IR, NMR), and impurity profiling. A detailed Certificate of Analysis (COA) is supplied with each shipment, and we can support compliance with relevant regulatory frameworks upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.