Description

8-Bromo-3-Fluoro-2-Hydroxyquinoline is a high-purity, multi-functional halogenated quinoline derivative. This compound serves as a critical advanced pharmaceutical intermediate and a versatile organic synthesis building block. It is primarily utilized by research and development teams in the pharmaceutical, agrochemical, and material science industries for the synthesis of novel active compounds and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Research: Used in the development of new fungicides and herbicides, leveraging its halogenated quinoline core for bioactivity.
• Organic Light-Emitting Diodes (OLEDs): Serves as a potential ligand or core structure in the development of electron-transport or emissive materials.
• Coordination Chemistry & Catalysis: Acts as a chelating ligand for transition metals, useful in creating novel catalysts for organic transformations.
• Fluorescent Probe Synthesis: The quinoline scaffold is modified to create sensitive probes for biochemical sensing and imaging applications.
• Academic & Contract Research: Employed in medicinal chemistry programs for structure-activity relationship (SAR) studies and library synthesis.

Basic Information

Product Name	8-Bromo-3-Fluoro-2-Hydroxyquinoline
CAS No.	834883-96-4
Molecular Formula	C9H5BrFNO
Molecular Weight	242.05 g/mol
Synonyms	8-Bromo-3-fluoroquinolin-2-ol; 2-Hydroxy-8-bromo-3-fluoroquinoline; 3-Fluoro-8-bromo-2-hydroxyquinoline; 8-Bromo-3-fluoro-2(1H)-quinolinone; Quinolin-2-ol, 8-bromo-3-fluoro-; 834883-96-4
EINECS	Contact for details

Quality Control

Our 8-Bromo-3-Fluoro-2-Hydroxyquinoline is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We support cGMP standards for pharmaceutical applications and can accommodate custom purity requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.