Description

2-Methyl-4-(Quinolin-2-Yl)But-3-Yn-2-Ol is a high-purity, advanced pharmaceutical intermediate characterized by its unique alkyne-substituted quinoline structure. This compound matters as a critical building block in the synthesis of complex molecules, offering a versatile handle for further chemical modifications via click chemistry or cross-coupling reactions. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), particularly for therapeutic areas requiring sophisticated heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, especially those targeting neurological or oncological pathways.
• Agrochemical Research: Used in the development of new generation pesticides and herbicides that require specific quinoline-based active components.
• Material Science: Acts as a monomer or functional additive in the creation of specialty polymers and advanced organic electronic materials.
• Chemical Synthesis: Provides a versatile alkyne functionality for Huisgen cycloaddition (click chemistry) and Sonogashira coupling reactions in complex molecule assembly.
• Academic & R&D: Employed in university and corporate research laboratories for methodological studies and the exploration of new chemical spaces.

Basic Information

Product Name	2-Methyl-4-(Quinolin-2-Yl)But-3-Yn-2-Ol
CAS No.	831235-64-4
Molecular Formula	C₁₄H₁₃NO
Molecular Weight	211.26 g/mol
Synonyms	2-Methyl-4-(2-quinolyl)but-3-yn-2-ol; 4-(Quinolin-2-yl)-2-methylbut-3-yn-2-ol; 2-Methyl-4-(quinolin-2-yl)but-3-yn-2-ol; 2-Methyl-4-(2-quinolinyl)-3-butyn-2-ol; 3-Butyn-2-ol, 2-methyl-4-(2-quinolinyl)-; 2-Methyl-4-(quinolin-2-yl)but-3-yn-2-ol (CAS 831235-64-4)
EINECS	Contact for details

Quality Control

Our 2-Methyl-4-(Quinolin-2-Yl)But-3-Yn-2-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for your most demanding R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider maintaining the material under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.