Description

6-Iodo-2,4-Dimethoxyquinazoline is a high-purity, functionalized quinazoline derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of complex molecules, particularly in pharmaceutical research and agrochemical discovery. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce iodine functionality for further cross-coupling reactions or structural diversification.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of targeted small molecule drugs, particularly kinase inhibitors and other biologically active quinazoline-based compounds.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators that utilize the quinazoline scaffold.
• Material Science: Building block for creating functional organic materials, such as organic light-emitting diodes (OLEDs) or charge-transport materials.
• Chemical Biology & Proteomics: Serves as a tagging or labeling reagent due to the reactive iodine handle for bioconjugation strategies.
• Academic & Contract Research: Essential for methodological development in organic chemistry, including studies on palladium-catalyzed cross-coupling reactions like Suzuki, Sonogashira, or Buchwald-Hartwig amination.
• Dye & Pigment Synthesis: Intermediate for the preparation of complex heterocyclic dyes and colorants.

Basic Information

Product Name	6-Iodo-2,4-Dimethoxyquinazoline
CAS No.	830343-15-2
Molecular Formula	C₁₀H₉IN₂O₂
Molecular Weight	316.10 g/mol
Synonyms	2,4-Dimethoxy-6-iodoquinazoline; 6-Iodo-2,4-bis(methoxy)quinazoline; Quinazoline, 6-iodo-2,4-dimethoxy-; 830343-15-2; 6-Iodo-2,4-dimethoxy-quinazoline
EINECS	Contact for details

Quality Control

Every batch of 6-Iodo-2,4-Dimethoxyquinazoline is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our standard offering meets high-purity research-grade specifications, typically ≥95% (HPLC). A comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation (by IR and NMR), and impurity profile is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.