Description

(5R,7R,8S)-5,6,7,8-Tetrahydro-2,6,6,8-Tetramethyl-5,7-Methanoquinoline is a high-purity, stereochemically defined synthetic intermediate of significant interest in advanced organic synthesis. Its value lies in its rigid, polycyclic structure which serves as a versatile chiral building block for the development of complex molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for applications in asymmetric catalysis, medicinal chemistry, and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-infective agents.
• Asymmetric Catalyst Ligand: Serves as a core structure for developing proprietary chiral ligands used in enantioselective synthesis.
• Agrochemical Research: Building block for creating new, stereospecific pesticides and herbicides with improved efficacy and environmental profiles.
• Material Science: Potential monomer or additive for advanced polymers where its rigid, fused-ring system can impart specific thermal or mechanical properties.
• Academic & Industrial R&D: Used in methodological studies and process chemistry development for constructing complex nitrogen-containing heterocycles.
• Flavor & Fragrance Synthesis: Intermediate for the production of sophisticated aroma chemicals with nuanced olfactory characteristics.

Basic Information

Product Name	(5R,7R,8S)-5,6,7,8-Tetrahydro-2,6,6,8-Tetramethyl-5,7-Methanoquinoline
CAS No.	828249-45-2
Molecular Formula	C₁₅H₂₁N
Molecular Weight	215.33 g/mol
Synonyms	(5R,7R,8S)-5,6,7,8-Tetrahydro-2,6,6,8-tetramethyl-5,7-methanoquinoline; 5,7-Methanoquinoline, 5,6,7,8-tetrahydro-2,6,6,8-tetramethyl-, (5R,7R,8S)-; Tetramethyl-methanoquinoline; Chiral methanoquinoline derivative; (5R,7R,8S)-Tetrahydrotetramethylmethanoquinoline; 828249-45-2; (5R,7R,8S)-Isomer of THTMQ
EINECS	Contact for details

Quality Control

Our (5R,7R,8S)-5,6,7,8-Tetrahydro-2,6,6,8-Tetramethyl-5,7-Methanoquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure high chemical and stereochemical purity suitable for demanding synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storage under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.