Description

1-(5-Bromopyridin-2-Yl)Cyclopropanecarboxylic Acid is a high-value brominated pyridine derivative that serves as a critical building block in modern synthetic chemistry. Its unique structure, featuring both a cyclopropane ring and a halogenated heterocycle, makes it an essential intermediate for constructing complex molecules with targeted biological activity. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the pyridine and cyclopropane motifs.
• Ligand and Catalyst Development: Serves as a sophisticated building block for creating novel ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of advanced organic electronic materials and functional polymers.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	1-(5-Bromopyridin-2-Yl)Cyclopropanecarboxylic Acid
CAS No.	827628-42-2
Molecular Formula	C9H8BrNO2
Molecular Weight	242.07 g/mol
Synonyms	1-(5-Bromo-2-pyridinyl)cyclopropanecarboxylic acid; Cyclopropanecarboxylic acid, 1-(5-bromo-2-pyridinyl)-; 1-(5-Bromopyridin-2-yl)cyclopropane-1-carboxylic acid; 2-(5-Bromopyridin-2-yl)cyclopropanecarboxylic acid (tautomer); 5-Bromo-2-(1-carboxycyclopropyl)pyridine
EINECS	Contact for details

Quality Control

Our production of 1-(5-Bromopyridin-2-Yl)Cyclopropanecarboxylic Acid adheres to stringent quality management protocols. Each batch is characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and oxidizing agents. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.