Description

4(3H)-Quinazolinone, 2-Chloro-6,7-Dimethoxy-5-Methyl- is a high-purity, synthetically valuable heterocyclic building block. This compound is a key intermediate in the research and development of novel pharmaceutical agents, particularly in the synthesis of kinase inhibitors and other biologically active molecules. It is essential for medicinal chemistry researchers and fine chemical manufacturers in the pharmaceutical and agrochemical industries seeking to develop new therapeutic candidates.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of targeted small-molecule drugs, especially kinase inhibitors for oncology and inflammatory diseases.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Agrochemical Development: Used in the research and synthesis of new active ingredients for crop protection products.
• Biochemical Tool Compound: Employed in biochemical assays to study enzyme function and cellular signaling pathways.
• Fine Chemical Synthesis: Acts as a specialized building block for the custom synthesis of complex organic molecules in contract research and manufacturing (CRO/CMO).

Basic Information

Product Name	4(3H)-Quinazolinone, 2-Chloro-6,7-Dimethoxy-5-Methyl-
CAS No.	827605-45-8
Molecular Formula	C₁₁H₁₁ClN₂O₃
Molecular Weight	254.67 g/mol
Synonyms	2-Chloro-6,7-dimethoxy-5-methylquinazolin-4(3H)-one; 2-Chloro-5-methyl-6,7-dimethoxy-4(3H)-quinazolinone; 5-Methyl-2-chloro-6,7-dimethoxy-4(3H)-quinazolinone; 6,7-Dimethoxy-5-methyl-2-chloro-4(3H)-quinazolinone; 2-Chloro-6,7-dimethoxy-5-methyl-3,4-dihydroquinazolin-4-one; 827605-45-8; Quinazolinone derivative, 2-chloro-6,7-dimethoxy-5-methyl-
EINECS	Contact for details

Quality Control

Our 4(3H)-Quinazolinone, 2-Chloro-6,7-Dimethoxy-5-Methyl- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.