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5-(Difluoromethyl)[1,2,4]Triazolo[1,5-A]Pyrimidin-7-Ol CAS NO 827587-45-1


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CAS No.:827587-45-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

5-(Difluoromethyl)[1,2,4]Triazolo[1,5-A]Pyrimidin-7-Ol is a high-purity, heterocyclic organic compound featuring a fused triazolopyrimidine core with a difluoromethyl substituent. This advanced chemical intermediate is valued for its unique structural motif, which imparts specific electronic and steric properties critical for modern synthetic chemistry. It is primarily utilized by research institutions and pharmaceutical development teams engaged in the discovery and synthesis of novel active ingredients, particularly in agrochemical and medicinal chemistry applications where fluorinated heterocycles are essential.

Application

  • Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, especially in the development of kinase inhibitors and other targeted therapies.
  • Agrochemical Research: Used as a core scaffold for developing new generations of fungicides and herbicides, leveraging the bioactivity of the triazolopyrimidine ring.
  • Chemical Synthesis: Acts as a versatile precursor for further functionalization, enabling the creation of complex molecular libraries for high-throughput screening.
  • Material Science Research: Investigated for potential use in the development of specialty chemicals and advanced materials due to its fluorinated heterocyclic structure.

Basic Information

Product Name 5-(Difluoromethyl)[1,2,4]Triazolo[1,5-A]Pyrimidin-7-Ol
CAS No. 827587-45-1
Molecular Formula C7H5F2N5O
Molecular Weight 213.15 g/mol
Synonyms 5-(Difluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-ol; 5-(Difluoromethyl)-7-hydroxy-[1,2,4]triazolo[1,5-a]pyrimidine; 7-Hydroxy-5-(difluoromethyl)[1,2,4]triazolo[1,5-a]pyrimidine; [1,2,4]Triazolo[1,5-a]pyrimidin-7-ol, 5-(difluoromethyl)-; DFMTP; 827587-45-1
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Quality Control

Our production of 5-(Difluoromethyl)[1,2,4]Triazolo[1,5-A]Pyrimidin-7-Ol adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical characterization, including HPLC for assay and purity, NMR for structural confirmation, and Karl Fischer titration for moisture content. Certificates of Analysis (COA) detailing all test results are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; therefore, containers should be kept sealed to minimize exposure to atmospheric moisture.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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