Description

4,7-Methano-1H-Indene-1,3-Dimethanol,Octahydro-,(1R,3S,3Ar,4S,7R,7As)-Rel-(9Ci) is a high-purity, stereochemically defined advanced intermediate with significant value in complex organic synthesis. Its rigid, polycyclic structure makes it a versatile chiral building block for constructing pharmacologically active molecules and specialty materials. This compound is primarily sought by pharmaceutical R&D and fine chemical industries for developing new active pharmaceutical ingredients (APIs) and high-performance polymers.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral therapeutic areas.
• Asymmetric Catalysis Ligand Precursor: Used to develop sophisticated chiral ligands and organocatalysts for enantioselective synthesis.
• Advanced Material Synthesis: Serves as a core monomer for producing specialty polymers with unique thermal and mechanical properties.
• Agrochemical Research: Employed in the development of new, stereospecific active ingredients for crop protection.
• Academic & Industrial R&D: A valuable tool for methodological development in organic chemistry and material science laboratories.
• Flavor & Fragrance Industry: Potential use as a precursor for complex, high-value aroma chemicals.

Basic Information

Product Name	4,7-Methano-1H-Indene-1,3-Dimethanol,Octahydro-,(1R,3S,3Ar,4S,7R,7As)-Rel-(9Ci)
CAS No.	827042-44-4
Molecular Formula	C13H20O2
Molecular Weight	208.30 g/mol
Synonyms	(1R,3S,3aR,4S,7R,7aS)-Octahydro-4,7-methano-1H-indene-1,3-dimethanol; Rel-(1R,3S,3aR,4S,7R,7aS)-Octahydro-4,7-methano-1H-indene-1,3-dimethanol; Bicyclo[2.2.1]heptane-2,5-dimethanol derivative; endo,endo-2,5-Bis(hydroxymethyl)bicyclo[2.2.1]heptane (specific stereoisomer); Norbornane dimethanol derivative; CAS 827042-44-4; Chiral norbornane diol
EINECS	Contact for details

Quality Control

Every batch of this advanced intermediate is produced under strict quality management systems. We employ state-of-the-art analytical techniques, including chiral HPLC, GC, and NMR, to ensure exceptional stereochemical purity and chemical identity. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF Titration)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.