Description

Benzo[B]Thiophene-2-Carboxylic Acid, 3-(Trifluoromethyl)- is a high-value, fluorinated heterocyclic building block essential for advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceuticals and agrochemicals, where the trifluoromethyl group imparts desirable metabolic stability and lipophilicity. It is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and material science industries for creating new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing properties of the trifluoromethyl-thiophene moiety.
• Material Science Research: Serves as a precursor for the development of advanced organic electronic materials, such as semiconductors for OLEDs or organic photovoltaics (OPVs).
• Ligand and Catalyst Development: Employed in the creation of specialized ligands for catalysis or as a scaffold for metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target engagement.
• Custom Synthesis and Contract Manufacturing: A key starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Item	Detail
Product Name	Benzo[B]Thiophene-2-Carboxylic Acid, 3-(Trifluoromethyl)-
CAS No.	826995-51-1
Molecular Formula	C10H5F3O2S
Molecular Weight	246.21 g/mol
Synonyms	3-(Trifluoromethyl)benzo[b]thiophene-2-carboxylic acid; 3-(Trifluoromethyl)-1-benzothiophene-2-carboxylic acid; 3-Trifluoromethylbenzo[b]thiophene-2-carboxylic Acid; 2-Benzothiophenecarboxylic acid, 3-(trifluoromethyl)-; 3-Trifluoromethyl-2-benzothiophenecarboxylic acid
EINECS	Contact for details

Quality Control

Our Benzo[B]Thiophene-2-Carboxylic Acid, 3-(Trifluoromethyl)- is produced under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for research and scale-up activities. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.