Description

(2S)-2-(Methylsulfonylmethyl)Pyrrolidine is a high-purity chiral building block and sulfone derivative of significant value in modern synthetic chemistry. Its unique structure, featuring a pyrrolidine ring with a methylsulfonylmethyl substituent, makes it a versatile intermediate for constructing complex molecules with precise stereochemistry. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the asymmetric synthesis of drug candidates, particularly those targeting neurological and metabolic disorders.
• Agrochemical Research: Used in the development of novel herbicides and pesticides where specific stereochemistry is crucial for bioactivity.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing novel chiral ligands and organocatalysts used in enantioselective transformations.
• Peptidomimetics and Proline Analogs: The pyrrolidine core makes it valuable for creating modified amino acids and peptide mimics for medicinal chemistry.
• Material Science Research: Investigated as a monomer or functional additive in the synthesis of specialized polymers.
• Academic and R&D Laboratories: Employed in methodological studies and the discovery of new synthetic pathways in organic chemistry.

Basic Information

Product Name	(2S)-2-(Methylsulfonylmethyl)Pyrrolidine
CAS No.	825644-58-4
Molecular Formula	C6H13NO2S
Molecular Weight	163.24 g/mol
Synonyms	(S)-2-(Methylsulfonylmethyl)pyrrolidine; (2S)-2-(Methanesulfonylmethyl)pyrrolidine; L-Proline, 2-[(methylsulfonyl)methyl]-; Pyrrolidine, 2-[(methylsulfonyl)methyl]-, (2S)-; (S)-2-((Methylsulfonyl)methyl)pyrrolidine; (S)-2-(Methylsulfonylmethyl) pyrrolidine; (S)-2-(Methylsulfonylmethyl)-pyrrolidine; (S)-2-(Methylsulfonylmethyl) pyrrolidine
EINECS	Contact for details

Quality Control

Our (2S)-2-(Methylsulfonylmethyl)Pyrrolidine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for advanced synthetic applications. A detailed Certificate of Analysis (COA) providing batch-specific data for identity, purity, and enantiomeric excess is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.