Description

2-Phenyl-7-Trifluoromethyl-4-Quinolinol is a high-purity, functionalized quinoline derivative of significant interest in advanced organic synthesis. This compound matters as a versatile and critical building block for the development of novel pharmaceutical agents and specialty materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating compounds with targeted biological or physical properties.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and antimicrobials.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, where the trifluoromethyl and quinolinol groups can enhance bioactivity and environmental stability.
• Material Science: Acts as a monomer or functional additive in the creation of advanced polymers, liquid crystals, and organic electronic materials due to its rigid aromatic structure.
• Chemical Biology Probe: Utilized as a scaffold for designing fluorescent probes or enzyme inhibitors to study biological pathways and mechanisms.
• Catalyst Ligand Synthesis: The nitrogen and oxygen donor atoms make it a candidate for constructing novel ligands used in homogeneous catalysis.

Basic Information

Product Name	2-Phenyl-7-Trifluoromethyl-4-Quinolinol
CAS No.	825620-20-0
Molecular Formula	C₁₆H₁₀F₃NO
Molecular Weight	289.25 g/mol
Synonyms	7-(Trifluoromethyl)-2-phenyl-4-quinolinol; 2-Phenyl-7-(trifluoromethyl)quinolin-4-ol; 4-Hydroxy-2-phenyl-7-(trifluoromethyl)quinoline; 7-Trifluoromethyl-2-phenyl-4-hydroxyquinoline; 2-Phenyl-7-trifluoromethylquinolin-4-ol; 825620-20-0; 4-Quinolinol, 2-phenyl-7-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 2-Phenyl-7-Trifluoromethyl-4-Quinolinol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR), to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed batch-specific data are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.