Description

1-(8-Benzyl-3,8-Diaza-Bicyclo[3.2.1]Octan-3-Yl)-2,2,2-Trifluoroethanone is a high-value, synthetically complex trifluoroacetylated diazabicyclic compound. It serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block in modern organic synthesis. This compound is primarily required by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and receptor-targeted therapies.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides, leveraging its unique bicyclic and fluorinated structure for enhanced bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Fluorine Chemistry: A valuable substrate for introducing the trifluoroacetyl group into complex molecules, modifying their physicochemical properties.
• Academic & Contract Research: Used in university and CRO laboratories for methodological development and exploratory chemistry projects.

Basic Information

Item	Detail
Product Name	1-(8-Benzyl-3,8-Diaza-Bicyclo[3.2.1]Octan-3-Yl)-2,2,2-Trifluoroethanone
CAS No.	824982-18-5
Molecular Formula	C16H18F3N2O
Molecular Weight	311.32 g/mol
Synonyms	8-Benzyl-3-(2,2,2-trifluoroacetyl)-3,8-diazabicyclo[3.2.1]octane; 3,8-Diazabicyclo[3.2.1]octane, 8-benzyl-3-(2,2,2-trifluoroacetyl)-; 1-(8-Benzyl-3,8-diazabicyclo[3.2.1]oct-3-yl)-2,2,2-trifluoroethanone; 8-Benzyl-3-trifluoroacetyl-3,8-diazabicyclo[3.2.1]octane; Trifluoroacetylated 8-Benzyl-3,8-diazabicyclooctane; Bn-DABCO Trifluoroacetamide Derivative
EINECS	Contact for details

Quality Control

Our 1-(8-Benzyl-3,8-Diaza-Bicyclo[3.2.1]Octan-3-Yl)-2,2,2-Trifluoroethanone is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full traceability are provided for each lot. We support development and cGMP-grade production to meet the stringent requirements of pharmaceutical and advanced R&D applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.