Description

Di-o-Methyldemethoxycurcumin is a synthetic derivative of curcumin, engineered to enhance stability and bioavailability for advanced research and development applications. This compound is valued for its potent biological activity and serves as a key intermediate or reference standard in the development of novel therapeutic agents and functional ingredients. It is primarily targeted towards the pharmaceutical, nutraceutical, and life science research industries, where high-purity, well-characterized chemical entities are essential for innovation and product development.

Application

• Pharmaceutical Research & Development: As a key intermediate or active pharmaceutical ingredient (API) precursor in the synthesis of novel anti-inflammatory, antioxidant, and neuroprotective agents.
• Reference Standard: For analytical method development, validation, and quality control in laboratories to ensure the purity and identity of related curcuminoid compounds.
• Nutraceutical Formulation: As a high-potency bioactive component in advanced dietary supplements targeting specific health and wellness pathways.
• Biochemical Research: For in vitro and in vivo studies investigating cellular signaling pathways, enzyme inhibition, and molecular mechanisms of action.
• Cosmeceutical Development: Incorporated into premium skincare formulations for its potential antioxidant and skin-protective properties.
• Chemical Synthesis: Serving as a versatile building block for the creation of new chemical entities with modified pharmacological profiles.

Basic Information

Item	Details
Product Name	Di-o-Methyldemethoxycurcumin
CAS No.	824951-60-2
Molecular Formula	C23H24O6
Molecular Weight	396.44 g/mol
Synonyms	Bisdemethoxycurcumin Dimethyl Ether; Di-O-Methylbisdemethoxycurcumin; 1,7-Bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione dimethyl ether; Curcumin III dimethyl ether; (1E,6E)-1,7-Bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione dimethyl ether; Di-O-methylated curcumin analog; Tetrahydrocurcumin dimethyl ether derivative
EINECS	Contact for details

Quality Control

Our Di-o-Methyldemethoxycurcumin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis. We provide a Certificate of Analysis (COA) with every shipment, detailing all specifications and test results to ensure compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is light-sensitive (store away from light). For long-term storage, consider inert gas purging or desiccant use to maintain stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.