Description

1H-Imidazo[4,5-C]Quinoline-1-Propanamine,4-Amino-2-(Ethoxymethyl) is a high-purity, advanced pharmaceutical intermediate belonging to the imidazoquinoline class of heterocyclic compounds. This compound is of significant commercial interest for its role as a key building block in the synthesis of novel therapeutic agents, particularly in the fields of immunology and antiviral research. Research and development teams in the global pharmaceutical and biotechnology sectors require this material for its precise chemical structure to develop next-generation treatments.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of Toll-like receptor (TLR) agonists and other immunomodulatory drug candidates.
• Antiviral Drug Research: Used in the development of novel compounds targeting viral infections.
• Oncology Research: Serves as a scaffold for creating potential small-molecule therapies in cancer immunotherapy.
• Chemical Biology: Employed as a probe or labeled compound in studying immune response pathways.
• Process Chemistry & Scale-Up: Supplied for route development and optimization from laboratory to pilot plant scale.
• Reference Standard: Used as a high-purity analytical standard for quality control and regulatory filings.

Basic Information

Product Name	1H-Imidazo[4,5-C]Quinoline-1-Propanamine,4-Amino-2-(Ethoxymethyl)
CAS No.	823809-16-1
Molecular Formula	C₁₅H₂₀N₄O
Molecular Weight	272.35 g/mol
Synonyms	4-Amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quinoline-1-propanamine; 1-Propanamine, 1H-imidazo[4,5-c]quinoline-4-amino-2-(ethoxymethyl)-; TLR7/8 Agonist Intermediate; Imiquimod-related intermediate; 4-Amino-α-2-(ethoxymethyl)-1H-imidazo[4,5-c]quinoline-1-ethanamine (alternate naming)
EINECS	Contact for details

Quality Control

Our 1H-Imidazo[4,5-C]Quinoline-1-Propanamine,4-Amino-2-(Ethoxymethyl) is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent controls for residual solvents and impurities. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment to ensure traceability and compliance with your research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.