Description

1-Naphthalenol,1,4,4A,5,6,7,8,8A-Octahydro-1,2,5,5,8A-Pentamethyl-,(1R,4As,8Ar)-Rel-(9Ci) is a high-purity, stereochemically defined octahydronaphthalenol derivative, a key chiral intermediate in advanced organic synthesis. Its value lies in its complex, rigid molecular framework, which serves as a versatile building block for creating sophisticated target molecules with precise three-dimensional structures. This compound is essential for R&D and production chemists in the pharmaceutical, agrochemical, and specialty fragrance industries, where it is used to develop novel active ingredients and high-value fine chemicals.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of complex drug candidates, particularly in steroid-mimetic and terpenoid-based therapeutic agents.
• Agrochemical Research: Used as a precursor in developing novel pesticides and herbicides, leveraging its polycyclic structure for biological activity.
• Fragrance & Flavor Chemistry: Serves as a starting material for synthesizing high-value, musky or ambery odorants with unique olfactory profiles.
• Material Science Research: Investigated as a monomer or modifying agent for creating specialized polymers with tailored thermal or optical properties.
• Catalyst & Ligand Development: Its stereogenic centers make it a candidate for developing chiral ligands used in asymmetric catalysis.
• Academic & Industrial R&D: A valuable tool for methodological studies in total synthesis and natural product chemistry.

Basic Information

Product Name	1-Naphthalenol,1,4,4A,5,6,7,8,8A-Octahydro-1,2,5,5,8A-Pentamethyl-,(1R,4As,8Ar)-Rel-(9Ci)
CAS No.	823785-68-8
Molecular Formula	C15H26O
Molecular Weight	222.37 g/mol
Synonyms	(1R,4aS,8aR)-1,2,5,5,8a-Pentamethyl-1,4,4a,5,6,7,8,8a-octahydronaphthalen-1-ol; rel-(1R,4aS,8aR)-1,2,5,5,8a-Pentamethyl-1,2,3,4,4a,5,6,7,8,8a-decahydronaphthalen-1-ol; Octahydronaphthalenol derivative; Pentamethyloctahydronaphthalenol; Chiral Decalin Derivative
EINECS	Contact for details

Quality Control

Every batch of this advanced intermediate is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and stereochemical integrity, which are critical for your synthetic applications. Certificates of Analysis (COA) detailing specifications such as chiral purity (HPLC), enantiomeric excess, and impurity profiles are available upon request and are aligned with cGMP principles for pharmaceutical-grade materials.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C for long-term stability. This compound is easily oxidized and light-sensitive; prolonged exposure to air, moisture, or light should be avoided to maintain purity and prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e.
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.