Description

5,7-Methanoquinoline-2-Methanol, 5,6,7,8-Tetrahydro-6,6-Dimethyl-, (5S,7S)- is a high-purity, stereochemically defined advanced pharmaceutical intermediate. This compound matters for its role as a critical chiral building block in the synthesis of complex active pharmaceutical ingredients (APIs), where its specific stereochemistry is essential for biological activity. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development and production of novel therapeutic agents, particularly within the fields of oncology and antiviral research.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of complex drug candidates, particularly those targeting specific biological pathways.
• Organic Synthesis Building Block: Used in research and development for constructing novel heterocyclic compounds and complex molecular architectures.
• Asymmetric Catalysis Research: Serves as a substrate or ligand precursor in studies exploring new catalytic methodologies.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize the potency and selectivity of lead compounds.
• Reference Standard: Used as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	5,7-Methanoquinoline-2-Methanol, 5,6,7,8-Tetrahydro-6,6-Dimethyl-, (5S,7S)-
CAS No.	821799-09-1
Molecular Formula	C14H19NO
Molecular Weight	217.31 g/mol
Synonyms	(5S,7S)-5,6,7,8-Tetrahydro-6,6-dimethyl-5,7-methanoquinoline-2-methanol; (5S,7S)-6,6-Dimethyl-5,6,7,8-tetrahydro-5,7-methanoquinoline-2-methanol; (5S,7S)-Tetrahydro-6,6-dimethyl-5,7-methanoquinoline-2-methanol; (5S,7S)-THDMMQM; Chiral Methanoquinoline Derivative; 2-(Hydroxymethyl)-5,6,7,8-tetrahydro-6,6-dimethyl-5,7-methanoquinoline (S,S-isomer)
EINECS	Contact for details

Quality Control

Our 5,7-Methanoquinoline-2-Methanol, 5,6,7,8-Tetrahydro-6,6-Dimethyl-, (5S,7S)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.