Description

Ethanone, 1-[(5S,7S)-5,6,7,8-Tetrahydro-6,6-dimethyl-5,7-methanoquinolin-2-yl]- is a high-purity, advanced pharmaceutical intermediate with a complex, stereochemically defined molecular architecture. This compound is critical for the synthesis of novel therapeutic agents, offering researchers and manufacturers a reliable building block for complex organic transformations. It is primarily utilized in the research and development of active pharmaceutical ingredients (APIs) within the pharmaceutical and fine chemical industries, where precise stereochemistry and consistent quality are paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and synthesis of novel drug candidates, particularly in medicinal chemistry programs.
• Organic Synthesis Building Block: Used in complex multi-step syntheses, including cycloaddition and coupling reactions, to construct intricate molecular frameworks.
• Asymmetric Catalysis Research: Serves as a precursor or ligand in the development of new catalytic systems due to its rigid, three-dimensional structure.
• Agrochemical Development: Potential application in the synthesis of advanced, stereoselective crop protection agents.
• Academic & Industrial R&D: A valuable compound for chemical research in universities and corporate R&D laboratories exploring new chemical entities.

Basic Information

Product Name	Ethanone, 1-[(5S,7S)-5,6,7,8-Tetrahydro-6,6-dimethyl-5,7-methanoquinolin-2-yl]-
CAS No.	821799-06-8
Molecular Formula	C17H19NO
Molecular Weight	253.34 g/mol
Synonyms	1-[(5S,7S)-5,6,7,8-Tetrahydro-6,6-dimethyl-5,7-methanoquinolin-2-yl]ethanone; (5S,7S)-2-Acetyl-5,6,7,8-tetrahydro-6,6-dimethyl-5,7-methanoquinoline; 2-Acetyl-5,6,7,8-tetrahydro-6,6-dimethyl-5,7-methanoquinoline (S,S-isomer); 821799-06-8; A chiral bridged quinoline ketone derivative.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency and high chemical purity. Quality is verified through comprehensive analytical techniques including HPLC, GC, NMR, and chiral analysis. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment. We support development under cGMP guidelines as required for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.