Description

Catasium(R) Mn(R)Rh, 2,3-Bis[(2R,5R)-2,5-Dimethylphospholanyl]Malein-n-Methylimide(1,5-Cyclooctadiene)Rhodium(I) Tetrafluoroborate is a high-purity, chiral organorhodium complex designed for advanced asymmetric catalysis. This product matters as it provides exceptional enantioselectivity and catalytic activity for the synthesis of optically active compounds, which are critical in modern fine chemical and pharmaceutical manufacturing. It is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-performance catalysts for hydrogenation and other transition metal-catalyzed reactions.

Application

• Asymmetric Hydrogenation Catalyst: For the enantioselective reduction of prochiral olefins, ketones, and imines in pharmaceutical intermediate synthesis.
• Chiral Ligand Precursor: Serves as a source of the chiral phospholane ligand framework for developing custom catalytic systems.
• Pharmaceutical API Synthesis: Enables the production of single-enantiomer active pharmaceutical ingredients (APIs) for drugs targeting CNS disorders, cardiovascular diseases, and anti-infectives.
• Agrochemical Intermediate Production: Used in the synthesis of chiral herbicides, fungicides, and plant growth regulators.
• Fine Chemical Manufacturing: Applied in the production of specialty flavors, fragrances, and advanced materials requiring high optical purity.
• Academic & Industrial R&D: A valuable tool for methodological development in organic synthesis and catalysis research.
• Process Chemistry Optimization: For scaling up enantioselective transformations from laboratory to pilot plant and commercial production.

Basic Information

Item	Details
Product Name	Catasium(R) Mn(R)Rh, 2,3-Bis[(2R,5R)-2,5-Dimethylphospholanyl]Malein-n-Methylimide(1,5-Cyclooctadiene)Rhodium(I) Tetrafluoroborate
CAS No.	821793-41-3
Molecular Formula	C₂₆H₄₃BF₄NO₂P₂Rh
Molecular Weight	657.29 g/mol
Synonyms	(R,R)-2,3-Bis(2,5-dimethylphospholano)maleimide(1,5-cyclooctadiene)rhodium(I) tetrafluoroborate; (R,R)-2,3-Bis[(2R,5R)-2,5-dimethylphospholanyl]maleimide(1,5-cyclooctadiene)rhodium tetrafluoroborate; Catasium® Mn(R)Rh Tetrafluoroborate; Rhodium(I) (2R,5R)-2,5-dimethylphospholane complex; Chiral DuPhos-type rhodium catalyst; (R,R)-Me-DuPhos Rh(COD) BF4; Asymmetric hydrogenation catalyst Rh-Me-DuPhos; Rh-(R,R)-Me-DuPhos(COD)BF4
EINECS	Contact for details

Quality Control

Every batch of Catasium(R) Mn(R)Rh Tetrafluoroborate is manufactured and tested under strict quality management systems to ensure consistency and high catalytic performance. Our standard quality protocol includes verification of identity, chiral purity, and rhodium content. Certificates of Analysis (COA) are provided with each shipment, detailing key specifications such as assay, enantiomeric excess (ee) of the ligand, and levels of metallic impurities. We support compliance with cGMP and ISO 9001 standards for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C. This compound is easily oxidized and light-sensitive; prolonged exposure to air, moisture, or ambient light will degrade its catalytic activity. The storage area should be cool, dry, and well-ventilated.

Specification

Item	Specification
Appearance	Orange to red crystalline powder
Identification (IR)	Conforms to structure
Assay (Rh content)	≥ 15.6% (w/w)
Purity (HPLC)	≥ 98.0%
Chiral Purity (ee of ligand)	≥ 99.0%
Solubility	Soluble in dichloromethane, THF; sparingly soluble in toluene

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.