Description

Chloro[(S)-(-)-5,5'-Dichloro-6,6'-Dimethoxy-2,2'-Bis(Diphenylphosphino)-1,1'-Biphenyl](p-Cymene)Ruthenium(II) Chloride CH2Cl2 Adduct is a high-purity, chiral ruthenium complex designed for advanced asymmetric catalysis. This compound is valued for its exceptional enantioselectivity and catalytic efficiency in key synthetic transformations. It is an essential catalyst for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to produce optically active intermediates.

Application

• Asymmetric Hydrogenation: A highly effective catalyst for the enantioselective reduction of prochiral olefins, ketones, and imines, critical for producing single-enantiomer pharmaceutical actives.
• Pharmaceutical Intermediate Synthesis: Enables the construction of chiral centers in complex drug molecules, including APIs for cardiovascular, CNS, and oncological treatments.
• Agrochemical Manufacturing: Used in the synthesis of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Facilitates the manufacture of specialty chemicals, flavors, and fragrances requiring high optical purity.
• Academic & Process R&D: A valuable tool for methodology development and scaling up novel asymmetric catalytic processes in academic and industrial laboratories.
• Chiral Ligand Evaluation: Serves as a pre-formed metal complex for studying and optimizing the performance of the associated (S)-BINAP-derived phosphine ligand system.

Basic Information

Product Name	Chloro[(S)-(-)-5,5'-Dichloro-6,6'-Dimethoxy-2,2'-Bis(Diphenylphosphino)-1,1'-Biphenyl](p-Cymene)Ruthenium(II) Chloride CH2Cl2 Adduct
CAS No.	821793-35-5
Molecular Formula	C55H48Cl4O2P2Ru • (CH2Cl2)x
Molecular Weight	Contact for details
Synonyms	(S)-(-)-RuCl[(p-cymene)(BINAP)]Cl•CH2Cl2; Dichloro(p-cymene)[(S)-(-)-5,5'-dichloro-6,6'-dimethoxy-2,2'-bis(diphenylphosphino)-1,1'-biphenyl]ruthenium(II) Dichloromethane Adduct; (S)-RuCl2(p-cymene)(BINAP)•CH2Cl2; (S)-(-)-RuCl[(p-cymene)(BINAP)]Cl•CH2Cl2; (S)-(-)-RuCl[(p-cymene)(5,5'-Dichloro-6,6'-dimethoxyBINAP)]Cl•CH2Cl2; (S)-(-)-RuCl[(p-cymene)(Dichloro-dimethoxyBINAP)]Cl•CH2Cl2; (S)-(-)-RuCl[(p-cymene)(Cl-MeOBIPHEP)]Cl•CH2Cl2; Ruthenium(II) (S)-(-)-5,5'-Dichloro-6,6'-dimethoxy-2,2'-bis(diphenylphosphino)-1,1'-biphenyl (p-cymene) chloride adduct
EINECS	Contact for details

Quality Control

Our Chloro[(S)-(-)-5,5'-Dichloro-6,6'-Dimethoxy-2,2'-Bis(Diphenylphosphino)-1,1'-Biphenyl](p-Cymene)Ruthenium(II) Chloride CH2Cl2 Adduct is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral assay, NMR for structural confirmation, and elemental analysis to ensure compliance with exacting R&D and process chemistry standards. Comprehensive Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere for long-term stability. The material is light-sensitive (store away from light). Allow the sealed container to reach ambient temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Orange to red-brown crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Solvent Content (NMR)	1-2 mol eq. CH2Cl2
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.