Description

(1S,2S)-1,2-Bis(4-Methoxyphenyl)Ethylenediamine Dihydrochloride is a high-purity chiral diamine salt, a critical building block in asymmetric synthesis. Its value lies in its role as a versatile ligand and resolving agent for the production of enantiomerically pure pharmaceutical intermediates. This compound is essential for research and manufacturing chemists in the pharmaceutical, agrochemical, and fine chemical industries who require high stereochemical control.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and cardiovascular diseases.
• Catalyst Ligand: Used as a chiral ligand in asymmetric hydrogenation and other transition metal-catalyzed reactions to induce high enantioselectivity.
• Chiral Resolution Agent: Employed for the separation of racemic mixtures of carboxylic acids and other acidic compounds via diastereomeric salt formation.
• Agrochemical Synthesis: Serves as a building block for creating enantiopure herbicides, fungicides, and plant growth regulators.
• Advanced Material Research: Investigated for the development of chiral polymers, metal-organic frameworks (MOFs), and liquid crystals with specific optical properties.

Basic Information

Product Name	(1S,2S)-1,2-Bis(4-Methoxyphenyl)Ethylenediamine Dihydrochloride
CAS No.	820965-96-6
Molecular Formula	C₁₆H₂₂Cl₂N₂O₂
Molecular Weight	345.26 g/mol
Synonyms	(1S,2S)-(-)-1,2-Bis(4-methoxyphenyl)ethylenediamine Dihydrochloride; (S,S)-1,2-Bis(4-methoxyphenyl)ethylenediamine Dihydrochloride; (1S,2S)-DACH-4-OMe Dihydrochloride; (S,S)-DACH-4-OMe Dihydrochloride; (1S,2S)-(-)-1,2-Diamino-1,2-bis(4-methoxyphenyl)ethane Dihydrochloride; (S,S)-DPEN-4-OMe Dihydrochloride; (1S,2S)-Bis(4-methoxyphenyl)ethylenediamine Dihydrochloride
EINECS	Contact for details

Quality Control

Our (1S,2S)-1,2-Bis(4-Methoxyphenyl)Ethylenediamine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, to ensure compliance with high-purity standards for research and pharmaceutical applications. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to prevent exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.