Description

Spiro[1,3-Dioxolane-2,5-[5H]Inden]-1-Ol, Octahydro-7A-Methyl-, (1S,3Ar,7As)- (9Ci) is a high-purity, stereochemically defined spirocyclic compound that serves as a valuable chiral building block and synthetic intermediate. Its unique fused-ring structure containing a dioxolane moiety makes it particularly useful for constructing complex molecular architectures with precise stereochemical control. This compound is essential for researchers and process chemists in the pharmaceutical and advanced materials sectors who require reliable, high-quality intermediates for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, particularly for central nervous system (CNS) targets.
• Asymmetric Synthesis: Employed as a building block in catalytic asymmetric reactions to introduce complex stereocenters.
• Ligand and Catalyst Development: Used in the synthesis of novel chiral ligands and organocatalysts for enantioselective transformations.
• Material Science Research: Serves as a precursor for developing specialty polymers and organic electronic materials with specific optical properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Process Chemistry: Integrated into scalable synthetic routes for the production of advanced fine chemicals under GMP conditions where applicable.

Basic Information

Product Name	Spiro[1,3-Dioxolane-2,5-[5H]Inden]-1-Ol, Octahydro-7A-Methyl-, (1S,3Ar,7As)- (9Ci)
CAS No.	820962-41-2
Molecular Formula	C12H18O3
Molecular Weight	210.27 g/mol
Synonyms	(1S,3aR,7aS)-Octahydro-7a-methylspiro[1,3-dioxolane-2,5'-inden]-1-ol; (1S,3aR,7aS)-7a-Methyloctahydrospiro[1,3-dioxolane-2,5'-inden]-1-ol; Spiro[1,3-dioxolane-2,5'-[5H]inden]-1-ol, octahydro-7a-methyl-, (1S,3aR,7aS)-rel-; (1S,3aR,7aS)-rel-Octahydro-7a-methylspiro[1,3-dioxolane-2,5'-inden]-1-ol; Spirocyclic dioxolane-indanol derivative; Chiral spiro-dioxolane intermediate
EINECS	Contact for details

Quality Control

Our Spiro[1,3-Dioxolane-2,5-[5H]Inden]-1-Ol, Octahydro-7A-Methyl-, (1S,3Ar,7As)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure high chemical and stereochemical purity suitable for demanding synthetic applications. Certificates of Analysis (COA) detailing identity, assay, impurity profile, and specific rotation are provided with every shipment. We support development and commercial projects with consistent quality and reliable supply.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider inert gas purging to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Specific Rotation	Provided on COA
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.