Description

1,3-Dioxaspiro[4.4]Non-7-En-6-One, 9-Hydroxy-7-(Hydroxymethyl)-2,2-Dimethyl-, (5R,9R)-Rel- (9Ci) is a high-value, stereochemically defined spirocyclic compound that serves as a critical chiral building block in advanced organic synthesis. Its unique fused dioxaspiro structure and dual hydroxyl functionality make it an indispensable intermediate for constructing complex molecular architectures with precise stereocontrol. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals. CAS No. 819070-94-5.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug candidates, particularly in antiviral, anticancer, and neurological therapeutic areas.
• Agrochemical Research: Used in the development of novel, stereoselective pesticides and herbicides where specific spatial orientation is crucial for bioactivity.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing sophisticated chiral ligands and organocatalysts.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of specialty chemicals, flavors, and fragrances requiring high stereochemical purity.
• Academic & Process Chemistry: A valuable tool for methodological development in organic chemistry and for scaling up stereoselective transformations.
• Material Science Research: Potential monomer or cross-linker for creating novel polymers with specific chiral or functional properties.

Basic Information

Product Name	1,3-Dioxaspiro[4.4]Non-7-En-6-One, 9-Hydroxy-7-(Hydroxymethyl)-2,2-Dimethyl-, (5R,9R)-Rel- (9Ci)
CAS No.	819070-94-5
Molecular Formula	C10H14O5
Molecular Weight	214.22 g/mol
Synonyms	rel-(5R,9R)-9-Hydroxy-7-(hydroxymethyl)-2,2-dimethyl-1,3-dioxaspiro[4.4]non-7-en-6-one; (5R,9R)-rel-9-Hydroxy-7-(hydroxymethyl)-2,2-dimethyl-1,3-dioxaspiro[4.4]non-7-en-6-one; 1,3-Dioxaspiro[4.4]non-7-ene-6,9-diol, 7-(hydroxymethyl)-2,2-dimethyl-, (5R,9R)-rel-; Spirocyclic Dihydroxy Lactone Derivative; Chiral Spiroketal Lactone Intermediate
EINECS	Contact for details

Quality Control

Our production of this advanced chiral intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency and high chemical purity. Identity and purity are confirmed through a suite of analytical techniques including HPLC, chiral chromatography, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing chiral purity, chemical assay, and impurity profile is provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de (diastereomeric excess)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.