Description

2-(5-((3-Methyloxetan-3-Yl)Methoxy)-1H-Benzo[D]Imidazol-1-Yl)Quinolin-8-Yl Trifluoromethanesulfonate is a high-value, complex heterocyclic compound featuring a benzimidazole-quinoline core functionalized with a methyloxetane group and a triflate leaving group. This molecular architecture makes it a critical advanced pharmaceutical intermediate (API) and a versatile building block in modern organic synthesis. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and advanced materials sectors for the development of novel active compounds.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly in oncology and antiviral research.
• Agrochemical Research: Used as a building block for developing new generation pesticides and herbicides with targeted activity.
• Organic Synthesis Reagent: Acts as an electrophile in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) due to the reactive triflate group.
• Ligand & Catalyst Development: The benzimidazole-quinoline scaffold is valuable for creating novel ligands in catalytic systems and metal-organic frameworks (MOFs).
• Material Science: Investigated for use in the development of organic semiconductors and luminescent materials.

Basic Information

Product Name	2-(5-((3-Methyloxetan-3-Yl)Methoxy)-1H-Benzo[D]Imidazol-1-Yl)Quinolin-8-Yl Trifluoromethanesulfonate
CAS No.	816463-39-5
Molecular Formula	C22H18F3N3O5S
Molecular Weight	493.46 g/mol
Synonyms	8-Quinolinyl 2-[5-[(3-methyl-3-oxetanyl)methoxy]-1H-benzimidazol-1-yl]-, trifluoromethanesulfonate; 2-(5-((3-Methyloxetan-3-yl)methoxy)-1H-benzo[d]imidazol-1-yl)quinolin-8-yl triflate; Quinoline-8-yl triflate benzimidazole derivative; 816463-39-5; Trifluoromethanesulfonic acid 2-[5-[(3-methyl-3-oxetanyl)methoxy]-1H-benzimidazol-1-yl]-8-quinolinyl ester
EINECS	Contact for details

Quality Control

Our 2-(5-((3-Methyloxetan-3-Yl)Methoxy)-1H-Benzo[D]Imidazol-1-Yl)Quinolin-8-Yl Trifluoromethanesulfonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and structural identity. Certificates of Analysis (COA) with detailed chromatographic data are provided to support your R&D and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment. For long-term storage, consider using desiccants or an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.