Description

2'-Trifluoromethyl-Biphenyl-4-Ylamine Hydrochloride is a high-purity, advanced pharmaceutical intermediate and organic building block. This compound is valued for its role in the synthesis of complex molecules, particularly in medicinal chemistry and agrochemical research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the trifluoromethyl group for enhanced biological activity and metabolic stability.
• Material Science: Serves as a precursor for functional materials, including liquid crystals and organic light-emitting diodes (OLEDs), due to its biphenyl core and fluorine substitution.
• Chemical Synthesis: Versatile reagent in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) for constructing complex biaryl and amine-containing structures in academic and industrial laboratories.
• Dye & Pigment Industry: Intermediate for producing specialized dyes and pigments where the amine group allows for further functionalization.

Basic Information

Product Name	2'-Trifluoromethyl-Biphenyl-4-Ylamine Hydrochloride
CAS No.	811842-57-6
Molecular Formula	C13H11ClF3N
Molecular Weight	273.68 g/mol
Synonyms	4-Amino-2'-(trifluoromethyl)biphenyl hydrochloride; [1,1'-Biphenyl]-4-amine, 2'-(trifluoromethyl)-, hydrochloride; 2'-(Trifluoromethyl)[1,1'-biphenyl]-4-amine hydrochloride; 2'-Trifluoromethylbiphenyl-4-ylamine hydrochloride; 4-Amino-2'-trifluoromethylbiphenyl HCl; 2'-Trifluoromethyl-4-aminobiphenyl hydrochloride; (2'-Trifluoromethyl-biphenyl-4-yl)-amine hydrochloride
EINECS	Contact for details

Quality Control

Our 2'-Trifluoromethyl-Biphenyl-4-Ylamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, impurities, and other critical parameters are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using a desiccator or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%; Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.