Description

1-n-Boc-2-(Aminomethyl)-3,4-Dihydroquinoline Hydrochloride is a high-purity, protected amine derivative used as a critical building block in advanced organic synthesis. This compound is essential for the development of complex molecules, particularly in pharmaceutical research and development. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel heterocyclic scaffolds and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel quinoline-based drug candidates targeting various therapeutic areas.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies due to its versatile protected amine functionality.
• Peptidomimetic Synthesis: Serves as a constrained scaffold for designing and synthesizing peptide mimics with enhanced metabolic stability.
• Agrochemical Development: Employed in the research and synthesis of new crop protection agents and pesticides.
• Chemical Biology Probes: Utilized in the creation of molecular probes for studying biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for CDMOs (Contract Development and Manufacturing Organizations) producing specialized fine chemicals.

Basic Information

Product Name	1-n-Boc-2-(Aminomethyl)-3,4-Dihydroquinoline Hydrochloride
CAS No.	811842-15-6
Molecular Formula	C₁₆H₂₁ClN₂O₂
Molecular Weight	308.80 g/mol
Synonyms	1-[(tert-Butoxycarbonyl)-2-(aminomethyl)-3,4-dihydroquinoline Hydrochloride; 2-(Aminomethyl)-1-Boc-1,2,3,4-tetrahydroquinoline Hydrochloride; tert-Butyl 2-(aminomethyl)-3,4-dihydroquinoline-1(2H)-carboxylate Hydrochloride; 1-Boc-2-(aminomethyl)-1,2,3,4-tetrahydroquinoline HCl; N-Boc-2-(aminomethyl)-1,2,3,4-tetrahydroquinoline Hydrochloride; 1-N-Boc-2-(aminomethyl)-3,4-dihydroquinoline HCl; 811842-15-6; Boc-Aminomethyl-DHQ HCl
EINECS	Contact for details

Quality Control

Our 1-n-Boc-2-(Aminomethyl)-3,4-Dihydroquinoline Hydrochloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. All batches are accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP (current Good Manufacturing Practice) guidelines where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.