Description

4-((4-Bromo-2-Fluorophenyl)Amino)-7-Methoxyquinazolin-6-Yl Acetate is a high-purity, advanced pharmaceutical intermediate belonging to the quinazoline class of compounds. This compound is of significant value for its role as a key building block in the research and development of targeted therapeutic agents, particularly kinase inhibitors. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of novel drug candidates for oncology and other disease areas.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of potent kinase inhibitors for targeted cancer therapies.
• Biochemical Research: Used as a reference standard or a starting material in academic and industrial research focused on signal transduction pathways and enzyme inhibition studies.
• Drug Discovery & Development: Serves as a core scaffold for medicinal chemists to explore structure-activity relationships (SAR) and develop new chemical entities (NCEs).
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing organizations (CMOs) for producing high-value, complex molecules under cGMP conditions.

Basic Information

Item	Details
Product Name	4-((4-Bromo-2-Fluorophenyl)Amino)-7-Methoxyquinazolin-6-Yl Acetate
CAS No.	808762-62-1
Molecular Formula	C17H13BrFN3O3
Molecular Weight	406.21 g/mol
Synonyms	4-[(4-Bromo-2-fluorophenyl)amino]-7-methoxy-6-quinazolinyl acetate; 6-Acetoxy-4-((4-bromo-2-fluorophenyl)amino)-7-methoxyquinazoline; 808762-62-1; 4-(4-Bromo-2-fluoroanilino)-7-methoxyquinazolin-6-yl acetate; 7-Methoxy-4-((4-bromo-2-fluorophenyl)amino)quinazolin-6-yl acetate
EINECS	Contact for details

Quality Control

Every batch of 4-((4-Bromo-2-Fluorophenyl)Amino)-7-Methoxyquinazolin-6-Yl Acetate is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the identity, purity, and consistency of the product meet the exacting standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) with HPLC purity, NMR, and MS data is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.