Description

Spiro[2H-1-Benzopyran-2,2-[1,3]Oxathiolane], 3,4-Dihydro-5-Methyl-, (2R,5S)- (9Ci) is a high-purity, stereochemically defined spirocyclic compound with the CAS number 807366-43-4. This molecule is a valuable chiral building block and intermediate, prized for its unique fused-ring structure that incorporates both benzopyran and oxathiolane motifs. It is primarily utilized by research and development teams in the pharmaceutical and advanced materials sectors for the synthesis of novel active pharmaceutical ingredients (APIs), functional dyes, and molecular switches.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new therapeutic agents, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Organic Synthesis Building Block: Used in asymmetric synthesis and medicinal chemistry for constructing complex, stereochemically rich molecular architectures.
• Photochromic Material Research: Acts as a precursor or model compound in the development of advanced photochromic and thermochromic materials for optical data storage and smart windows.
• Ligand and Catalyst Development: Employed in the design of novel chiral ligands and organocatalysts for enantioselective transformations.
• Academic and Industrial R&D: Essential for fundamental chemical research in universities and corporate laboratories exploring spirocyclic chemistry and heterocyclic compounds.
• Fine Chemical Production: Used in the pilot-scale and commercial-scale synthesis of specialty chemicals requiring high enantiomeric purity.

Basic Information

Product Name	Spiro[2H-1-Benzopyran-2,2-[1,3]Oxathiolane], 3,4-Dihydro-5-Methyl-, (2R,5S)- (9Ci)
CAS No.	807366-43-4
Molecular Formula	C12H14O2S
Molecular Weight	222.30 g/mol
Synonyms	(2R,5S)-3,4-Dihydro-5-methylspiro[2H-1-benzopyran-2,2'-[1,3]oxathiolane]; (2R,5S)-5-Methyl-3,4-dihydro-2H,2'H-spiro[benzopyran-2,2'-[1,3]oxathiolane]; 5-Methyl-3,4-dihydrospiro[2H-1-benzopyran-2,2'-[1,3]oxathiolane], (2R,5S)-; Spiro[2H-1-benzopyran-2,2'-[1,3]oxathiolane], 3,4-dihydro-5-methyl-, (2R,5S)-; (R,S)-Dihydro-methyl-spirobenzopyran-oxathiolane; Chiral spirobenzopyran-oxathiolane derivative
EINECS	Contact for details

Quality Control

Our production of Spiro[2H-1-Benzopyran-2,2,[1,3]Oxathiolane], 3,4-Dihydro-5-Methyl-, (2R,5S)- (9Ci) adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, to ensure high chemical and isomeric purity. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We support cGMP and ISO 9001 compliant manufacturing for advanced research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); prolonged exposure to air, moisture, or light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.