Description

Spiro[2H-1-Benzopyran-2,2-[1,3]Oxathiolane], 3,4-Dihydro-5-Methyl-, (2S,5S)- (9Ci) is a high-purity, stereochemically defined spirocyclic compound that serves as a critical chiral building block and advanced intermediate in sophisticated organic synthesis. Its unique fused benzopyran-oxathiolane structure offers significant value for constructing complex molecular architectures with precise stereochemical control. This compound is essential for research and development chemists in the pharmaceutical and fine chemical industries, particularly for applications in medicinal chemistry, asymmetric catalysis, and the development of novel functional materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), especially in central nervous system (CNS) and cardiovascular drug candidates.
• Asymmetric Synthesis: Utilized as a sophisticated ligand precursor or chiral auxiliary in catalytic asymmetric reactions to induce high enantioselectivity.
• Material Science Research: Investigated as a core component for developing novel photochromic or electrochromic materials due to its spirobenzopyran moiety.
• Organic Electronics: Potential building block for organic semiconductors and conductive polymers where specific molecular geometry and electronic properties are required.
• Agrochemical Synthesis: Intermediate in the development of advanced, stereospecific pesticides and herbicides.
• Academic & Industrial R&D: Serves as a valuable reference standard and starting material for methodological studies in synthetic organic chemistry.

Basic Information

Product Name	Spiro[2H-1-Benzopyran-2,2-[1,3]Oxathiolane], 3,4-Dihydro-5-Methyl-, (2S,5S)- (9Ci)
CAS No.	807366-40-1
Molecular Formula	C12H14O2S
Molecular Weight	222.30 g/mol
Synonyms	(2S,5S)-3,4-Dihydro-5-methylspiro[2H-1-benzopyran-2,2'-[1,3]oxathiolane]; (2S,5S)-5-Methyl-3,4-dihydro-2H,2'H-spiro[benzopyran-2,2'-[1,3]oxathiolane]; 5-Methyl-3,4-dihydrospiro[2H-1-benzopyran-2,2'-[1,3]oxathiolane], (2S,5S)-; Spiro[2H-1-benzopyran-2,2'-[1,3]oxathiolane], 3,4-dihydro-5-methyl-, (2S,5S)-; (S,S)-Dihydro-5-methylspiro[benzopyran-oxathiolane]; Chiral spirobenzopyran-oxathiolane derivative.
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Quality Control

Every batch of Spiro[2H-1-Benzopyran-2,2,[1,3]Oxathiolane], 3,4-Dihydro-5-Methyl-, (2S,5S)- (9Ci) is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and enantiomeric purity consistent with research-grade standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under an inert atmosphere when appropriate for prolonged exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.