Description

Spiro[Isobenzofuran-1(3H),2-[1,3]Oxathiolane], 5-Methyl-, (1S,5S)- (9Ci) is a high-purity, stereochemically defined spirocyclic compound that serves as a critical chiral building block in advanced organic synthesis. Its unique fused-ring structure, incorporating both isobenzofuran and oxathiolane moieties, makes it a valuable intermediate for constructing complex molecular architectures with precise stereochemical control. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, particularly where specific spatial orientation is crucial for biological activity.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, especially in central nervous system (CNS) and antiviral therapeutic areas.
• Agrochemical Synthesis: Used in the creation of advanced, stereoselective pesticides and herbicides where the specific (1S,5S) configuration can influence efficacy and environmental profile.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for developing novel chiral ligands and organocatalysts used in enantioselective transformations.
• Material Science Research: Investigated as a monomer or building block for synthesizing specialty polymers with unique optical or electronic properties.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in spirocyclic and heterocyclic chemistry.

Basic Information

Product Name	Spiro[Isobenzofuran-1(3H),2-[1,3]Oxathiolane], 5-Methyl-, (1S,5S)- (9Ci)
CAS No.	807366-18-3
Molecular Formula	C11H10O2S
Molecular Weight	206.26 g/mol
Synonyms	(1S,5S)-5-Methylspiro[isobenzofuran-1(3H),2'-[1,3]oxathiolane]; 5-Methylspiro[isobenzofuran-1(3H),2'-[1,3]oxathiolane], (1S,5S)-; Spiro[isobenzofuran-1(3H),2'-[1,3]oxathiolane], 5-methyl-, (1S,5S)-; (1S,5S)-5-Methyl-1,3-dihydro-2-benzofuran-1-spiro-2'-(1',3'-oxathiolane); CAS 807366-18-3
EINECS	Contact for details

Quality Control

Our Spiro[Isobenzofuran-1(3H),2-[1,3]Oxathiolane], 5-Methyl-, (1S,5S)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and process development. Certificates of Analysis (COA) detailing identity, assay, enantiomeric excess, and impurity profiles are provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.