Description

1,7-Methano-1H-1-Benzazepin-5(2H)-One,9Alpha-Ethyl-3,4,5Abta,6,7,8,9,9Abta-Octahydro-,()-(8Ci) is a complex, polycyclic organic compound with a unique bridged benzazepine core structure, serving as a critical advanced intermediate in modern synthetic chemistry. Its precise stereochemistry and functional groups make it an invaluable building block for the research and development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and receptor-targeted therapies. This high-purity intermediate is essential for pharmaceutical R&D laboratories and fine chemical manufacturers seeking to develop next-generation therapeutic compounds with high specificity.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of complex drug candidates, especially those targeting neurological pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities (NCEs).
• Asymmetric Synthesis: Employed as a sophisticated scaffold or precursor in catalytic asymmetric reactions to introduce stereochemical complexity.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for methodological development in organic synthesis and the study of benzazepine chemistry.
• Precursor for Bioactive Molecules: Serves as a starting material for generating libraries of compounds for high-throughput screening (HTS) in drug discovery.

Basic Information

Product Name	1,7-Methano-1H-1-Benzazepin-5(2H)-One,9Alpha-Ethyl-3,4,5Abta,6,7,8,9,9Abta-Octahydro-,()-(8Ci)
CAS No.	802897-21-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	9α-Ethyl-1,7-methano-1H-1-benzazepin-5(2H)-one; 9α-Ethyl-1,7-methano-1H-1-benzazepin-5(2H)-one, octahydro-; 9α-Ethyl-3,4,5ab,6,7,8,9,9ab-octahydro-1,7-methano-1H-1-benzazepin-5(2H)-one; 9α-Ethyl-1,7-methanobenzazepin-5(2H)-one; 9α-Ethyloctahydro-1,7-methano-1H-1-benzazepin-5(2H)-one; (8Ci)-9α-Ethyl-1,7-methano-1H-1-benzazepin-5(2H)-one; CAS 802897-21-8
EINECS	Contact for details

Quality Control

Our production of this advanced pharmaceutical intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency and high purity. Quality is verified through a comprehensive suite of analytical techniques including HPLC, GC, NMR, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, and impurity profiles. We support our clients' regulatory needs with full traceability and documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to prevent any potential moisture uptake or contamination.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.