Description

6-Iodo-4-(3-Methoxyphenylamino)-8-Methylquinoline-3-Carboxamide is a sophisticated quinoline-based organic compound, identified by CAS number 801315-47-9, serving as a crucial advanced intermediate in pharmaceutical research and development. This compound matters for its role in the synthesis of targeted drug candidates, particularly in oncology and other therapeutic areas requiring complex heterocyclic scaffolds. It is primarily needed by R&D chemists and process development scientists in pharmaceutical, biotechnology, and fine chemical industries engaged in developing novel small-molecule therapies.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates targeting specific biological pathways.
• Kinase Inhibitor Research: Used in the development and optimization of potential kinase inhibitors due to the quinoline pharmacophore.
• Chemical Biology Probes: Serves as a precursor for creating molecular probes to study enzyme function and cellular signaling.
• Medicinal Chemistry SAR Studies: Employed in structure-activity relationship (SAR) studies to explore and optimize biological activity.
• Process Chemistry Development: Used in scaling up and optimizing synthetic routes for potential active pharmaceutical ingredients (APIs).
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in API manufacturing.

Basic Information

Item	Detail
Product Name	6-Iodo-4-(3-Methoxyphenylamino)-8-Methylquinoline-3-Carboxamide
CAS No.	801315-47-9
Molecular Formula	C18H16IN3O2
Molecular Weight	433.25 g/mol
Synonyms	6-Iodo-4-[(3-methoxyphenyl)amino]-8-methyl-3-quinolinecarboxamide; 4-(3-Methoxyanilino)-6-iodo-8-methylquinoline-3-carboxamide; 801315-47-9; 6-Iodo-4-(3-methoxyanilino)-8-methylquinoline-3-carboxamide; 3-Quinolinecarboxamide, 6-iodo-4-[(3-methoxyphenyl)amino]-8-methyl-; 4-(3-Methoxyphenylamino)-6-iodo-8-methylquinoline-3-carboxamide
EINECS	Contact for details

Quality Control

Our 6-Iodo-4-(3-Methoxyphenylamino)-8-Methylquinoline-3-Carboxamide is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP standards for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is light-sensitive and should be handled under appropriate conditions to maintain stability. Keep the container tightly sealed in a dry environment to prevent moisture uptake.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.