Description

3-(3-Carbamoyl-4-(3-Methoxyphenylamino)-8-methylquinolin-6-ylsulfonyl)benzoic acid is a high-purity, advanced pharmaceutical intermediate characterized by its complex quinoline-based molecular structure. This compound matters for its critical role in the research and development of novel therapeutic agents, particularly in targeted drug discovery programs. It is primarily needed by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in synthesizing complex bioactive molecules for oncology and other specialized therapeutic areas.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel small-molecule drug candidates, particularly for targeted therapies.
• Kinase Inhibitor Research: Used in the development and optimization of potential kinase inhibitors due to its quinoline sulfonamide scaffold.
• Chemical Biology Probes: Employed in the creation of molecular probes for studying specific biological pathways and protein interactions.
• Medicinal Chemistry: Provides a versatile core structure for structure-activity relationship (SAR) studies and lead compound optimization.
• Contract Research & Development (CRO): Supplied to CROs and academic institutions for proprietary drug discovery projects.
• High-Value Fine Chemical Synthesis: Integrated into multi-step synthetic routes for producing complex, high-value specialty chemicals.

Basic Information

Product Name	3-(3-Carbamoyl-4-(3-Methoxyphenylamino)-8-methylquinolin-6-ylsulfonyl)benzoic Acid
CAS No.	801311-41-1
Molecular Formula	C25H20N4O5S
Molecular Weight	488.51 g/mol
Synonyms	Benzoic acid, 3-[[3-(aminocarbonyl)-4-[(3-methoxyphenyl)amino]-8-methyl-6-quinolinyl]sulfonyl]-; 3-[(3-Carbamoyl-4-[(3-methoxyphenyl)amino]-8-methyl-6-quinolinyl)sulfonyl]benzoic Acid; 801311-41-1; 3-(3-Carbamoyl-4-(3-methoxyanilino)-8-methylquinoline-6-sulfonyl)benzoic acid; 6-Quinolinesulfonamide, N-(3-methoxyphenyl)-8-methyl-3-[[3-(carboxy)phenyl]sulfonyl]-4-; 3-({3-Carbamoyl-4-[(3-methoxyphenyl)amino]-8-methylquinolin-6-yl}sulfonyl)benzoic acid
EINECS	Contact for details

Quality Control

Our 3-(3-Carbamoyl-4-(3-Methoxyphenylamino)-8-methylquinolin-6-ylsulfonyl)benzoic acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure compliance with exacting R&D standards. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and analytical methods is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.