Description

1-Naphthalenol,1,2,3,4,4A,5,6,7-Octahydro-4,4A-Dimethyl-6-(1-Methylethyl)-,(1R,4R,4Ar,6R)-(9Ci) is a high-purity, stereochemically defined octahydronaphthalenol derivative, serving as a critical chiral intermediate in advanced organic synthesis. Its defined stereochemistry and functional group make it a valuable building block for constructing complex molecular architectures with high enantiomeric purity. This compound is essential for research and development in the pharmaceutical and fine chemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs) and specialty agrochemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug molecules, particularly in steroid-like or terpenoid-based therapeutic agents.
• Fine Chemical Synthesis: Used as a versatile building block in the preparation of specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Agrochemical Research: Employed in the development of novel pesticides and herbicides where the specific spatial arrangement of the molecule influences biological activity.
• Material Science Research: Investigated as a monomer or precursor for the synthesis of advanced polymers and liquid crystals with specific optical properties.
• Catalyst Ligand Development: The hydroxyl and chiral framework can be modified to create novel ligands for asymmetric catalysis.
• Academic & R&D: Serves as a standard or starting material in university and corporate research laboratories for methodological studies in stereoselective synthesis.

Basic Information

Product Name	1-Naphthalenol,1,2,3,4,4A,5,6,7-Octahydro-4,4A-Dimethyl-6-(1-Methylethyl)-,(1R,4R,4Ar,6R)-(9Ci)
CAS No.	800385-96-0
Molecular Formula	C15H26O
Molecular Weight	222.37 g/mol
Synonyms	(1R,4R,4aR,6R)-4,4a-Dimethyl-6-(propan-2-yl)-1,2,3,4,4a,5,6,7-octahydronaphthalen-1-ol; (1R,4R,4aR,6R)-6-Isopropyl-4,4a-dimethyl-1,2,3,4,4a,5,6,7-octahydronaphthalen-1-ol; (1R,4R,4aR,6R)-4,4a-Dimethyl-6-isopropyl-1,2,3,4,4a,5,6,7-octahydronaphthalen-1-ol; Octahydro-4,4a-dimethyl-6-(1-methylethyl)-1-naphthalenol (stereoisomer); Chiral Octahydronaphthalenol Derivative
EINECS	Contact for details

Quality Control

Our production of this chiral intermediate adheres to strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC, to ensure high chemical and enantiomeric purity suitable for demanding synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and impurity profiles. We support cGMP compliance for pharmaceutical applications, with documentation available to meet audit requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% e.e.
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.